von Johanna Sophie Lubasch ; Patrick Andreas Eder ; Christian Kaiser ; Andrea Diana Klausen ; Daniel Overheu ; Anja Partheymüller ; Asarnusch Rashid ; Simon Schäfer ; Maximilian Scharonow ; Insa Seeger
Online veröffentlicht: 8. März 2023 ; Gesehen am 17.09.2024
Artificial Intelligence; Cardiovascular disease; Data and biomaterial collection; German Centre for Cardiovascular Research; Medical Ethics; Research platform; Standardisation
The German Centre for Cardiovascular Research (DZHK) is one of the German Centres for Health Research and aims to conduct early and guideline-relevant studies to develop new therapies and diagnostics that impact the lives of people with cardiovascular disease. Therefore, DZHK members designed a collaboratively organised and integrated research platform connecting all sites and partners. The overarching objectives of the research platform are the standardisation of prospective data and biological sample collections among all studies and the development of a sustainable centrally standardised storage in compliance with general legal regulations and the FAIR principles. The main elements of the DZHK infrastructure are web-based and central units for data management, LIMS, IDMS, and transfer office, embedded in a framework consisting of the DZHK Use and Access Policy, and the Ethics and Data Protection Concept. This framework is characterised by a modular design allowing a high standardisation across all studies. For studies that require even tighter criteria additional quality levels are defined. In addition, the Public Open Data strategy is an important focus of DZHK. The DZHK operates as one legal entity holding all rights of data and biological sample usage, according to the DZHK Use and Access Policy. All DZHK studies collect a basic set of data and biosamples, accompanied by specific clinical and imaging data and biobanking. The DZHK infrastructure was constructed by scientists with the focus on the needs of scientists conducting clinical studies. Through this, the DZHK enables the interdisciplinary and multiple use of data and biological samples by scientists inside and outside the DZHK. So far, 27 DZHK studies recruited well over 11,200 participants suffering from major cardiovascular disorders such as myocardial infarction or heart failure. Currently, data and samples of five DZHK studies of the DZHK Heart Bank can be applied for.
Clinical research in cardiology Berlin : Springer, 2006 112(2023), 7, Seite 923-941 Online-Ressource
von Patrick Wagner ; Nils Strodthoff ; Patrick Wurzel ; Arturo Marban ; Sonja Scharf ; Hendrik Schäfer ; Philipp Seegerer ; Andreas Loth ; Sylvia Hartmann ; Frederick Klauschen ; Klaus-Robert Müller ; Wojciech Samek ; Martin-Leo Hansmann
von Anna Bergstermann ; Eva Cendon ; Luise B. Flacke ; Andreas Friedrich ; Christine Hiltergerke ; Miriam Schäfer ; Sabrina Strazny ; Fabienne Theis ; Nina Maria Wachendorf ; Kathrin Wetzel
Bonn Berlin: Bundesministerium für Bildung und Forschung
46 Seiten.
Literaturverzeichnis: Seite 40-43
Handreichung Lernergebnisse / herausgegeben durch: die wissenschaftliche Begleitung des Bund-Länder-Wettbewerbs "Aufstieg durch Bildung: offene Hochschulen", vertreten durch die Projektleitungen: Prof. Dr. Anke Hanft (Carl von Ossietzky Universität Oldenburg), Prof. Dr. Andrä Wolter (Humboldt-Universität zu Berlin), Prof. Dr. Ada Pellert (Deutsche Universität für Weiterbildung), Dr. Eva Cendon (Deutsche Universität für Weiterbildung)Handreichung der wissenschaftlichen Begleitung des Bund-Länder-Wettbewerbs "Aufstieg durch Bildung: offene Hochschulen"
Handreichung Lernergebnisse / herausgegeben durch: die wissenschaftliche Begleitung des Bund-Länder-Wettbewerbs "Aufstieg durch Bildung: offene Hochschulen", vertreten durch die Projektleitungen: Prof. Dr. Anke Hanft (Carl von Ossietzky Universität Oldenburg), Prof. Dr. Andrä Wolter (Humboldt-Universität zu Berlin), Prof. Dr. Ada Pellert (Deutsche Universität für Weiterbildung), Dr. Eva Cendon (Deutsche Universität für Weiterbildung) ; Teil 1;
